RESUMO Introdução: Há altas exigências para a qualidade física dos atletas chineses na ginástica moderna. Objetivos: Este trabalho tem como principal estudo verificar se a carga de trabalho dos ginastas chineses pode suportar o correspondente treinamento de alta intensidade no processo de treinamento. Métodos: Foram utilizados métodos de investigação científica experimental e análise estatística para efetuar um estudo de longo prazo sobre dezenas de ginastas nas escolas chinesas além de desenhar as curvas de carga de trabalho desses ginastas durante os exercícios. Tentamos determinar a correlação efetiva entre a carga de trabalho e o treinamento físico do atleta e sua forma corporal. Resultados: Durante o treinamento de alta intensidade dos ginastas chineses, os batimentos cardíacos puderam exceder brevemente os 190 batimentos por minuto. Conclusão: No processo de treinamento de diferentes ginastas, os batimentos cardíacos dos ginastas apresentam diferenças óbvias. Portanto, o uso de estratégias de treinamento científicas e razoáveis pode efetivamente melhorar a capacidade do coração dos atletas afim de suportar cargas de exercício de alta intensidade e ajudar a melhorar o desempenho do ginasta. Nível de evidência II; Estudos terapêuticos - investigação dos resultados do tratamento.

ABSTRACT Introduction: In modern gymnastics, there are high demands for the physical quality of Chinese athletes. Objectives: This paper mainly studies whether the workload of Chinese gymnasts can support the corresponding high-intensity training in the training process. Methods: Experimental scientific research methods and statistical analysis are used to conduct a long-term study on dozens of gymnasts in Chinese schools and draw the workload curves of these gymnasts during gymnastic exercises. We try to determine the effective correlation between the athlete's body load and physical training and body shape. Results: During the training of gymnasts, heart rates can briefly exceed 190 beats per minute. Conclusion: In the training process of different gymnasts, the gymnasts’ heart rates show obvious differences. Therefore, the use of scientific and reasonable training strategies can effectively improve the ability of athletes’ hearts to withstand high-intensity exercise loads and help improve the gymnast's performance. Level of evidence II; Therapeutic studies - investigation of treatment results.

RESUMEN Introducción: La calidad física de los atletas chinos en la gimnasia moderna es muy exigente. Objetivos: El estudio principal de este trabajo es comprobar si la carga de trabajo de las gimnastas chinas puede soportar el correspondiente entrenamiento de alta intensidad en el proceso de entrenamiento. Métodos: Se utilizaron métodos de investigación científica experimental y análisis estadísticos para llevar a cabo un estudio a largo plazo sobre docenas de gimnastas de escuelas chinas, además de dibujar las curvas de carga de trabajo de estas gimnastas durante los ejercicios. Intentamos determinar la correlación efectiva entre la carga de trabajo y el entrenamiento físico y la forma del cuerpo del atleta. Resultados: Durante el entrenamiento de alta intensidad de las gimnastas chinas, las frecuencias cardíacas podían superar brevemente las 190 pulsaciones por minuto. Conclusión: En el proceso de entrenamiento de diferentes gimnastas, las frecuencias cardíacas de las gimnastas muestran diferencias evidentes. Por lo tanto, el uso de estrategias de entrenamiento científicas y razonables puede mejorar eficazmente la capacidad cardíaca de las atletas para soportar cargas de ejercicio de alta intensidad y ayudar a mejorar el rendimiento del gimnasta. Nivel de evidencia II; Estudios terapéuticos - investigación de los resultados del tratamiento.

RESUMO Objetivos Avaliar o potencial da aplicação da tecnologia de impressão 3D na medição da área de defeito ósseo acetabular em pacientes adultos diagnosticados com displasia do desenvolvimento do quadril (DDH). Métodos 23 casos de DDH que requereram cirurgia de substituição total do quadril foram incluídos neste estudo. O exame pré-operatório confirmou os filmes pélvicos padrão Crowe, incluindo 3 casos de Crowe I, 7 Crowe II, e 13 Crowe III. A tecnologia de impressão 3D foi utilizada para imprimir o modelo de quadril antes da operação. Com base no modelo pré-impresso, o planejamento pré-operatório e os procedimentos cirúrgicos foram estabelecidos. A área dos defeitos ósseos acetabulares foi medida, a prótese de tamanho selecionado foi registrada, e a cirurgia foi realizada (grupo A). A área do defeito ósseo acetabular real e o tamanho da prótese também foram registrados (grupo B). Resultados Os resultados comparativos indicaram que a área real do defeito acetabular medida intraoperativamente e a área medida usando a tecnologia de impressão 3D não diferiu significativamente para todos os participantes (todos P>0,05). Conclusão O modelo pré-operatório pode medir com precisão a área de defeito ósseo acetabular para DDH. É relevante desenvolver implantes individualizados para pacientes com DDH tratados com a técnica de impressão 3D. Nível de Evidência IV: Série de casos.

ABSTRACT Objectives Evaluate the application value of 3D printing technology in measuring acetabular bone defect area in adult patients diagnosed with developmental dysplasia of the hip (DDH). Methods 23 cases of DDH requiring total hip replacement surgery were enrolled in this study. Preoperative examination confirmed the standard pelvic plain films Crowe, including 3 cases of Crowe I, 7 Crowe II, and 13 Crowe III. The 3D printing technology was used to print the hip model before the operation. Based on the pre-printed model, pre-operative planning and surgical procedures were established. The area of the acetabular bone defects was measured, the selected size prosthesis was recorded, and the surgery was performed (group A). The actual acetabular bone defect area and the prosthesis size were also recorded (group B). Results The comparative results indicated that the actual acetabular defect area measured intraoperatively and the area measured using the 3D printing technology did not significantly differ for all participants (all P>0.05). Conclusion Preoperative model can accurately measure the acetabular bone defect area for DDH. It is significant to develop individualized implants for DDH patients treated with the 3D printing technique. Level of Evidence IV: Case series.

Lupus peritonitis (LP) is extremely rare. Acute LP is characterized by rapid onset of ascites and severe abdominal pain, in addition to other well-recognized clinical features of a general systemic lupus erythematosus (SLE) fare. Ascites associated with acute LP has been rarely reported as the prominent feature of a SLE fare. We report a 39-year-old woman who developed massive, painful ascites as the presenting manifestation of a SLE fare. Diagnostic workup ruled out the possibility of hepatic, cardiovascular, infectious, or malignant diseases, and confirmed the presence of a SLE fare. The patient was treated with methyl prednisolone and hydroxychloroquine resulting in dramatic improvement of her condition. During ambulatory follow up, she has remained asymptomatic up to the moment of this writing. Adrenal steroids and hydrocychloroquine may be useful for the management of SLE fares in patients with massive, painful ascites due to acute LP.

La peritonitis lúpica es rara. El cuadro agudo se caracteriza por ascitis de comienzo rápido, dolor abdominal severo y otras manifestaciones de una recidiva de un lupus eritematoso sistémico (LES). Sólo ocasionalmente e ha informado que la ascitis y peritonitis lúpica sean las principales manifestaciones de una recidiva lúpica. Presentamos a una mujer de 39 años que presentó ascitis masiva y dolorosa como la primera manifestación de una reactivación lúpica. El estudio diagnóstico descartó problemas hepáticos, pulmonares, cardiacos, cáncer o infecciones y confirmó la reactivación lúpica. La paciente se trató con metilprednisolona y cloroquina, resultando en una mejoría dramática. Al momento de preparar este informe, la paciente permanece asintomática en control ambulatorio. Los corticoides y cloroquina pueden ser medicamentos útiles para el tratamiento de pacientes con ascitis dolorosa y masiva secundaria a peritonitis lúpica.

Purpose Evidence shows that adenosine triphosphate (ATP) is involved in the transmission of multiple chronic pain via P2X7 receptor. This study was to investigate the P2X7 and microglial cells in the chronic prostatitis pain. Materials and Methods Rats were divided into control group and chronic prostatitis group (n = 24 per group). A chronic prostatitis animal model was established by injecting complete Freund's adjuvant (CFA) to the prostate of rats, and the thermal withdrawal latency (TWL) was detected on days 0, 4, 12 and 24 (n = 6 at each time point in each group). Animals were sacrificed and the pathological examination of the prostate, detection of mRNA expression of P2X7 and ionized calcium binding adaptor molecule 1 (IBA-1) and measurement of content of tumor necrosis factor-α (TNF-α) and interleukin-1β (IL-1β) in the dorsal horn of L5-S2 spinal cord were performed on days 0, 4, 12 and 24. In addition, the content of TNF-α and IL-1β in the dorsal horn of L5-S2 spinal cord was measured after intrathecal injection of inhibitors of microglial cells and/or P2X7 for 5 days. Results The chronic prostatitis was confirmed by pathological examination. The expression of P2X7 and IBA-1 and the content of TNF-α and IL-1β in rats with chronic prostatitis were significantly higher than those in the control group. On day 4, the expressions of pro-inflammatory cytokines became to increase, reaching a maximal level on day 12 and started to reduce on day 24, but remained higher than that in the control group. Following suppression of microglial cells and P2X7 receptor, the secretion of TNF-α and IL-1β was markedly reduced. Conclusion In chronic prostatitis pain, the microglial cells and P2X7 receptor are activated resulting in the increased expression of TNF-α and IL-1β in the L5-S2 spinal cord, which might attribute to the maintenance and intensification of pain in chronic prostatitis.

A spectrophotometric method for the simultaneous determination of norfloxacin, ofloxacin and lomefloxacin, is described. The spectrophotometric analysis is made possible with the aid of chemometric methods, such as classical least square (CLS), principal component regression (PCR), partial least square (PLS), and radial basis function-artificial neural network (RBF-ANN). Spectra were collected in the 190-400 nm range from a set of samples of three compounds in a Britton-Robinson buffer solution (pH=1.81). This approach overcomes the significant practical difficulties of severe spectral overlap. It was found that peak intensities are proportional to the concentration for each analyte. The obtained linear calibration concentration ranges are 0.6-13.8, 0.5-15.0, and 0.5-15.0 mg L-1 for norfloxacin, ofloxacin and lomefloxacin, respectively, and the LODs for the three analytes were found to be approximately 6-24x 10-2 mg L-1 . The proposed method was applied to a prediction set of synthetic mixtures of three analytes. The results were shown that the RBF-ANN model gave the best results (RPE T = 3.0%). This method was also applied for the determination of norfloxacin, ofloxacin and lomefloxacin in rabbit blood serum, and these compared well with those from the alternative analysis by HPLC.